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Three award winners and their dedicated research teams will each receive $1.1 million to advance our understanding of mental health conditions at a fundamental level.
Participants in the Better Mental Health Basics Program
MONTREAL, March 19, 2024 (GLOBE NEWSWIRE) — Brain Canada, the Krembill Foundation, and the Women’s Brain Health Initiative (WBHI) are proud to announce that in an effort to fund bold, transformative, basic mental health research projects, Erica The Legacy Foundation and Canada Power Corporation are proud to announce the winners of this award. The basics of a better mental health program.
Basic research is scientific research conducted primarily to expand knowledge and understanding rather than to directly address clinical or practical problems.of Basics of a mental health improvement program Investigating neuropathological changes and information processing disorders that may provide insight into the causes and development of mental health conditions and ultimately lead to new directions for treatment and intervention, Funds basic research investigating sex and gender roles.
By the time Canadians reach the age of 40, one in two will have or have experienced a mental health condition. More fundamental brain research is needed to understand how the brain functions not only when healthy but also when sick. In response to this need, Brain Canada and its donors and partners have invested a total of $3.3 million to support the three recipients and their research teams.
“Brain research plays an important role in improving our understanding of the causes and development of mental health conditions,” said Yaara Sachs, Minister of Mental Health and Addictions. Advancing Better Mental Health Programs – This initiative supports better mental health for all Canadians. ”
“Including sex-specific biological considerations helps us understand the biological causes of mental health conditions,” said Dr. Vivian Poupon, President and CEO of Brain Canada. To tell. “We are extremely proud to support her three recipients who are at the forefront of addressing gender differences in brain research.”
of Basics of improving mental health Recipients explore mental health conditions such as depression, anxiety, and postnatal depression, with an emphasis on gender-specific factors and differences.
“We know very little about the brain and the conditions that affect it,” said Mark Krembill, president and CEO of the Krembill Foundation. “These gaps in understanding result in clinical research focusing on symptoms rather than causes. Without basic research that takes gender differences into account to uncover disease mechanisms, the development of effective treatments will be difficult. We are proud to support this program and the vital research it funds.”
“By highlighting gender-specific factors and differences, these studies revolutionize the understanding and treatment of mental health conditions, ultimately paving the way for more effective interventions tailored to women’s unique needs. “It has great potential,” says founder and president Lynn Poslands. WBHI’s. “Through initiatives like this, we are making meaningful progress toward promoting brain health and well-being in women.”
Some of the bold projects supported by Brain Canada, the Krembil Foundation and WBHI include:
A new hypothesis of depression related to insulin resistance in the mesolimbic system and metabolic resistance due to obesity
Stephanie Beaugland of the University of Calgary was awarded $1.1 million.
This project explores whether the insulin deactivation associated with obesity and type 2 diabetes underlies the increased prevalence of depression and anxiety associated with these conditions, and whether insulin reversal could improve mental health. Investigate whether it can be improved. The study was co-authored by Marie-Ave Paquet and Rochelynn Dalangin of Université Laval, Stéphanie Fulton and collaborators of the University of Montreal, Carrie Ferrario of the University of Michigan, and Xiaochen Bai of the University of Texas Southwestern Medical Center. This will be carried out together with Mr.
Developing open science resources to map the transgenerational and gender-specific effects of perinatal neuropsychiatric disorders.
$1.1 million was awarded to Leesa Galea of the Center for Addiction and Mental Health.
This project aims to understand brain changes in postpartum depression and how a mother’s postpartum mental health predisposes her child to lifelong mental health conditions. The study will be conducted with collaborators Blaine Kalish from SickKids and Shreejoy Tripathy from the Center for Addiction and Mental Health.
Prodepressive dopamine receptor complexes in the brain mediate sex differences in depression and anxiety: Validation and strategies for drug discovery
Susan George of the University of Toronto was awarded $1.1 million.
This project aims to use animal models to investigate whether the dopamine receptor complex is involved in the high rates of depression in women, with the ultimate goal of drug discovery. The research will be carried out with co-researcher Martin Beaulieu. Collaborators include Junchao Tong and Isabelle Boileau of the Center for Addiction and Mental Health.
“Generous funding from Brain Canada will foster innovation, collaboration within our lab to understand the molecular biomarkers of postpartum depression, one of the highest risk periods for first-onset depression. and serve as a catalyst to drive breakthrough discoveries,” says Dr. Leesa. Galea. “We are honored to receive this funding for an under-studied area of research that impacts not only the health of birth parents but also the health of their families. We commend its funding partners.”
Learn more about the basics of a mental health improvement program.
Listen to Brain Canada’s mental health podcast. play with marbles.
This Brain Health Awareness Month, celebrate your most vital organ by gaining a deeper understanding of how the brain functions in health and disease.
This program is made possible by the Canadian Brain Research Fund (CBRF), an innovative arrangement between the Government of Canada (through Health Canada), the Brain Canada Foundation, the Krembill Foundation, and the Women’s Brain Health Initiative, and is supported by Erica Legacy. Foundation and Canadian Power Corporation.
About the Krembil Foundation
The Krembill Foundation is a Canadian family-led non-profit organization that supports medical research. The Foundation’s goal is to impact people’s lives through discoveries that accelerate research, expand knowledge, and ultimately lead to scientific advances in medicine. With this goal in mind, the Foundation is focusing its funding on historically underfunded areas such as neurodegenerative and autoimmune diseases. The Foundation supports research aimed at filling knowledge gaps and ultimately helping find treatments and cures for neurodegenerative diseases. www.krembilfoundation.ca
About the Women’s Brain Health Initiative
The Women’s Brain Health Initiative (WBHI), a Canadian philanthropic foundation founded in 2012, is the largest resource for evidence-based information on women’s brain health. This is an important force in raising critical awareness of unacceptable contradictions in brain research regarding distress that occurs at alarming rates in women. WBHI’s research, education, and awareness programs are essential to improving the brain health and mental health of women, their caregivers, and their families, and fund research to combat brain aging diseases that affect women. It is also essential to promote the urgency to invest. For more information, visit womensbrainhealth.org.
Media contact:
Brielle Goulart
Head of Communications & Marketing
brain canada
brielle.goulart@braincanada.ca
450-915-2253
A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/04efd86e-2878-4226-8496-e25677c3d783.
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